Centro Nacional de Análisis Genómico

The Centro Nacional de Análisis Genómico (CNAG-CRG) is a non-profit organization created in 2009 with the mission to carry out projects in DNA sequencing and analysis in collaboration with researchers from Catalonia, Spain and from the international research community.

The center is organized in two production-oriented units for Sequencing and Bioinformatics Analysis that secure seamless operation, and 6 research groups focused on Bioinformatics Tools Development, Applied Genomics and Genome Biology. The production groups cover a range of capabilities including whole-genome de novo sequencing, whole genome re-sequencing, targeted re-sequencing, profiling of mRNAs, epigenome sequencing, and single cell analysis.

The CNAG-CRG participates in large national and international collaborative research projects in areas as diverse as cancer, rare disorders, host-pathogen interactions, preservation of endangered species, evolutionary studies and improvement of species of agricultural interest, in collaboration with scientists from universities, hospitals, research centers and biotechnology companies. Scientists at CNAG-CRG contribute to projects in four major international initiatives: International Cancer Genome Consortium (ICGC), International Rare Diseases Research Consortium (IRDiRC), International Human Epigenome Consortium (IHEC), Human Cell Atlas (HCA).

Role within Screen4Care

Within Scree4Care, the CNAG-CRG will perform last generation genome sequencing and develop solutions for data collation, sharing, analysis and interpretation. The center has broad expertise in integrated genome-phenome data collation and analysis, and has developed tools that enable controlled discovery and access to pseudonymised genomic and clinical information from patients with rare diseases. The CNAG-CRG will contribute to S4C final objective of developing new strategies to advance rare disease research.